Ụbọchị Ọrịa ogbu na nkwonkwo ụwa 12 Ọkt 2022

Ụbọchị ọrịa ogbu na nkwonkwo nke ụwa bụ mmemme mmata ahụike zuru ụwa ọnụ nke a na-ahazi kwa afọ na 12 October iji mepụta mmata banyere ọrịa rheumatic na musculoskeletal, mmetụta ọ na-enwe na ndụ mmadụ na ịkụziri ndị mmadụ ihe mgbaàmà & mgbochi mgbochi na nduzi maka nchọpụta mmalite iji nagide nsogbu ọ bụla ọzọ. .

Mkpa nke World Arthritis Day (WAD)

Ọrịa ogbu na nkwonkwo bụ ọrịa nkwonkwo na-egbuke egbuke, nke na-emetụta anụ ahụ nkwonkwo gburugburu nkwonkwo, na anụ ahụ ndị ọzọ na-ejikọta ya, na-eme ka nkwonkwo mgbu na isi ike.Ihe karịrị ụdị ọrịa ogbu na nkwonkwo dị 100, ma ihe ka ọtụtụ bụ ọrịa ogbu na nkwonkwo na ọrịa ogbu na nkwonkwo.N'ihi enweghị mmata na nkwado, ọrịa ogbu na nkwonkwo na ọnọdụ ndị metụtara ya emebiwo ọtụtụ ndụ gburugburu ụwa.Enweghị ọgwụgwọ a kapịrị ọnụ maka ọrịa ogbu na nkwonkwo, nhọrọ ọgwụgwọ dịgasị iche dabere n'ụdị dị iche iche, yabụ ọ dị mkpa ịghọta akara & akara ma nweta nchoputa oge mbụ iji nweta ọgwụgwọ kwesịrị ekwesị.

Ụdị ọrịa ogbu na nkwonkwo kachasị

Ụdị ndị a na-ahụkarị gụnyere ọrịa ogbu na nkwonkwo (OA), ọrịa ogbu na nkwonkwo (RA), ọrịa ogbu na nkwonkwo psoriatic (PsA), fibromyalgia na gout.Ọrịa ogbu na nkwonkwo na ọrịa ndị metụtara ya nwere ike ịkpata ihe mgbu na-agbanwe ndụ na ụzọ dị iche iche.
Rheumatoid ogbu na nkwonkwo (RA) bụ otu n'ime ọrịa nkwonkwo na-efe efe na-emekarị, nke a na-ahụkarị na ụmụ nwanyị dị n'etiti.E gosipụtara nke ọma dị ka ọrịa ogbu na nkwonkwo na-adịghị ala ala, symmetrical, na-aga n'ihu.Na mgbakwunye na imetụta nkwonkwo, e nwere ọtụtụ ihe ngosipụta nke ọzọ, dị ka akpụkpọ ahụ, anya, obi, ngụgụ, usoro ọbara, wdg.

Ọnụnọ nke RA bụ 0.5-1%, yana nwanyị na nwoke ruru 3: 1.Ọ bụ 4 ruo 5 ugboro elu n'ime ndị inyom na-erubeghị afọ 50, ma mgbe afọ 60 gasịrị, ọnụọgụ na-aghọ ihe dịka 2 ruo 1.Ndị nwere ọrịa ogbu na nkwonkwo na-enwekarị protein C-reactive protein (CRP), nke nwere ike igosi ọnụnọ nke usoro mkpali n'ime ahụ.Nlele ọbara ndị ọzọ a na-ahụkarị na-achọ ihe rheumatoid factor (RF) na mgbochi cyclic citrullinated peptide (anti-CCP).

RA(Rheumatoid ogbu na nkwonkwo)

Rheumatoid ogbu na nkwonkwo bụ ọrịa mkpali na-adịghị ala ala nke nwere ike imetụta karịa naanị nkwonkwo gị.N'ime ụfọdụ ndị mmadụ, ọnọdụ ahụ nwere ike imebi usoro ahụ dị iche iche, gụnyere akpụkpọ ahụ, anya, ngụgụ, obi na arịa ọbara.

Ọrịa autoimmune, ọrịa ogbu na nkwonkwo na-apụta mgbe usoro ahụ ji alụso ọrịa ọgụ na-awakpo anụ ahụ nke gị n'ụzọ hiere ụzọ.

N'adịghị ka mmebi akwa na akwa nke ọrịa ogbu na nkwonkwo, ọrịa ogbu na nkwonkwo na-emetụta mkpuchi nke nkwonkwo gị, na-eme ka ọzịza na-egbu mgbu nke nwere ike mechaa mee ka ọkpụkpụ ọkpụkpụ na nrụrụ nkwonkwo.

Anti-CCP Anti-Cyclic Citrullinated Peptide Antibody

Anti-cyclic citrullinated peptide antibody (Anti-CCP): Ọ bụ iberibe polypeptide nke protein cyclic polyguanidine ma bụrụkwa ụdị mgbochi IgG.Anti-cyclic citrullinated peptide antibodies na-ezo onwe ya site na B lymphocytes nke ndị ọrịa nwere ọrịa ogbu na nkwonkwo (RA), ebe B lymphocytes nke ndị ọrịa nwere ọrịa ndị ọzọ na ndị nkịtị anaghị ezobe ezoghị ọnụ ọgwụ mgbochi cyclic citrullinated peptide mgbochi.Ya mere, ọ nwere mmetụta dị elu na nkọwa maka ọrịa ogbu na nkwonkwo, ọ bụkwa ihe na-egosi nke ọma maka nchọpụta mmalite nke ọrịa ogbu na nkwonkwo.

Anti-CCP (Anti-cyclic citrullinated peptides) bụ ụdị autoantibody: mgbochi nke na-arụ ọrụ megide mgbochi nkịtị nke ahụ gị.A na-emepụtakarị mgbochi CCP mgbe ị nwere ọrịa ogbu na nkwonkwo.Ndị a autoantibodies na-amalite ilekwasị anya na ịwakpo anụ ahụ dị mma.

Ihe ngosi nchọpụta mmalite nke ọrịa ogbu na nkwonkwo: anti-cyclic citrullinated antibodies na-apụta 1-10 afọ tupu ngosipụta ụlọ ọgwụ nke ọrịa ogbu na nkwonkwo, dabara maka nyocha anụ ahụ nke ndị nwere ahụike yana nyocha mmalite nke otu dị oke egwu.Ugbu a,ekwenyere na uche nke anti-cyclic citrullinated peptide antibodies maka nchoputa nke rheumatoid ogbu na nkwonkwo bụ 50% ka 78%, kpọmkwem bụ 96%, na nti ọnụego nke n'oge ọrịa nwere ike iru 80%.

AehealthAnti-CCP Pomume

Aehealth Anti-CCP (Anti-cyclic Citrullinated Peptide Antibody) Nnwale ọnụọgụ ngwa ngwa na-anabata usoro nyocha nke Immunofluorescence.

Usoro nchọpụta ihe mgbochi CCP bụ 10～500 U/mL;ọnụọgụ njikọ linear dị n'etiti ntinye uche nke usoro ihe ọmụma na ntinye a tụrụ atụ nwere ike iru r≥0.990.A na-eji ya na nyocha Aehealth Lamuno X immunofluorescence iji duga nyocha mmalite na nyocha ọgwụgwọ nke ndị ọrịa rheumatism.

Ihe mgbochi CCP na-emekọ ihe na paramita ọrụ RA.

Ihe mgbochi CCP na-ebu amụma mmebi RA.

Ọgwụ mgbochi CCP nwere ike ịba uru n'ịkpa oke ọrịa ogbu na nkwonkwo metụtara ịba ọcha n'anya C sitere na RA.